Dystonia is a neurological movements disorder characterized by maintained muscle contractions, abnormal muscle tension, and involuntary, agonizing muscle contractions. Statistics reveal that over 300, 1000 people in North America are afflicted by this disorder that is the third most common motion disorder after Parkinson’s disease and nerve tremors. These types of involuntary and frequently painful actions may affect either a single muscle or an entire group of muscles like those in the arms, neck, or thighs or even the complete body. People afflicted with dystonia usually have no associated psychiatric disorders and so they have normal intelligence. Medical marijuana
A couple of preclinical studies and case reviews investigating the use of medical cannabis to control the indications of dystonia, mostly these twisting and repetitive movements or unnatural postures are now available in recently published technological literature. The July concern of The Journal of Pain and Symptom Administration includes a 2002 case research that reports an improvement in the indications of dystonia after a 49 yr old patient anguish from chronic pain used to smoke medical marijuana. It absolutely was reported by investigators and medical scientists that the pain score (subjectively) dropped from an increased 9 to little or nothing (considering a 0-10 analog visual scale of pain) following the patient inhaled MMJ. In addition, the subject matter did not need additional analgesic medication for the next forty-eight hours.
Detectives concluded that there was no existing treatment plan or intervention to date that has produced such an overall dramatic improvement in the condition of person’s like these. The same results were obtained in a case study that was conducted on another 25 year old patient who had been battling from Wilson’s disease that triggered generalized dystonia. In the August 2004 concern of the journal Motion Disorders, an Argentinian research team documented their results of the person exhibiting significant clinical improvement after the inhalation of medical marijuana. In the same 12 months, a team of Spanish researchers at the Hannover Medical School administered 5 mg of the lively cannabinoid in medical weed called THC to a 38-year-old professional pianist.
The musician’s dystonia was efficiently treated following the government of any single dose of THC in this placebo handled trial. Researchers reported that prior to cannabinoid treatment; the patient was unresponsive to standard medications and therefore, was not a longer even executing publicly. However, there was a clear improvement of motor control in the damaged hand of the subject and the patient was also able to play technically demanding and complex literature just two hours following your intake of THC. The subject has not been able the play the same pieces of music ahead of the treatment process. These kinds of results evidently indicate that medical cannabis significantly takes away the symptoms of this type of dystonia called focal dystonia.
In 2002, a placebo-controlled randomized analysis that investigated the employment of Cesamet (a synthetic dental cannabinoid naboline) in 12-15 patients afflicted with segmental primary and generalized dystonia showed no significant improvement in their condition. Researchers concluded that this end result may be dose related and it has little or nothing to do with the efficacy of medical marijuana in helping patients manage their dystonia symptoms. Large doses of the natural non-psychoactive CBD (cannabinoid cannabidiol) and synthetic cannabinoids are known to moderate the progression of the disease in animals as suggested by at least one recent preclinical trial and further investigation about the use of cannabis and cannabinoids in humans is ongoing.